Millions of Americans have benefited from BOTOX, DYSPORT, and XEOMIN treatments to improve and prevent frown lines of the face, forehead lines, and crow’s feet around the eyes. Often wrinkles are creases that have been worn into the skin and subcutaneous tissue by making the same repeated expression over many years. The muscles causing these “expression lines” can be relaxed by blocking nerve impulses, which smooths away the wrinkles. The effects of these injectables last 3 to 4 months before a touch-up is needed.